Posts by: Joana Carvalho

Joana Carvalho

Joana holds a BSc in Biology, a MSc in Evolutionary and Developmental Biology and a PhD in Biomedical Sciences from Universidade de Lisboa, Portugal. Her work has been focused on the impact of non-canonical Wnt signaling in the collective behavior of endothelial cells — cells that made up the lining of blood vessels — found in the umbilical cord of newborns.

February 26, 2021February 26, 2021

Corneal Neurotization Surgery Doesn’t Guarantee Full Vision

News

Despite being successful, corneal neurotization — a surgical procedure that seeks to restore nerve function in the cornea — does not guarantee neurotrophic keratitis (NK) patients will fully regain their ... Read more

January 8, 2021January 8, 2021

Oxervate Found to Help Wound Healing, Improve Vision in Early Stage NK

News

Oxervate (cenegermin) can promote wound healing and improve visual acuity in patients at the earlier stages of neurotrophic keratitis (NK), a small pilot study found. However, treatment with the prescription eye ... Read more

November 20, 2020November 20, 2020

Plans Continue for Phase 2 Trial of Nasal Spray, OC-01, as NK Treatment

News

Plans to request that OC-01 (varenicline), Oyster Point Pharma‘s lead therapy candidate for a series of eye disorders, be cleared for testing in a Phase 2 trial in people with neurotrophic keratitis ... Read more

May 29, 2020May 29, 2020

Off-label Use of EGF Ointment Seen to Quickly Promote Corneal Healing

News

An ointment containing epidermal growth factor (EGF) — a small protein that stimulates the growth of cells making up the surface of different tissues — can promote tissue healing, improve ... Read more

May 15, 2020May 15, 2020

How Potential Eye Treatments Like RGN-259 Work Detailed in Study

News

Various mechanisms by which thymosin beta 4 (Tβ4) — a molecule currently being investigated to treat eye disorders that include dry eye syndrome and neurotrophic keratitis — promotes tissue healing and regeneration ... Read more

February 12, 2020February 12, 2021

NK Triggered in Boy by Nerve Damage During Brain Surgery

News

Damage to the trigeminal nerve — a large and complex nerve that controls tear production, and facial movement and sensation — during brain surgery led to neurotrophic keratitis (NK) developing in ... Read more

January 29, 2020January 29, 2021

Corneal Neurotization Techniques Healed NK Patients

News

Direct and indirect corneal neurotization — two different approaches of a surgical procedure that aims to restore nerve function in the cornea — both were able to fully heal patients ... Read more